Word: penicillins
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...something like a middle-ear infection, which is indeed caused by several different types of bacteria, including Pneumococcus. Left alone, a handful of these infections could lead to permanent hearing loss. And yet their treatment has, in just the past 10 years in the U.S., boosted the prevalence of penicillin-resistant pneumococci to more than...
...researchers have started to scour bacterial DNA for new and possibly better targets for drug development. The goal is to produce a compound that works so differently from today's antibiotics that germs won't know how to start developing resistance. Other research has produced drugs that help restore penicillin's ability to clobber resistant germs, provided the compounds are given in combination...
...antibiotic specifically approved by the FDA to treat anthrax, and suddenly it was the hottest drug in town. Doctors were besieged by patients demanding prescriptions "just in case," and pharmacies, particularly in New York, Washington and Florida, couldn't keep up. Other antibiotics, including doxycycline and that old standby penicillin, are just as effective against the particular strain that was showing up in tainted letters, and a few weeks later, when the cdc recommended that doctors switch to those, Cipro's days in the spotlight were over...
Doctors stress that the side effects of Cipro, one of the newest fluoroquinolones, are no worse than those of penicillin and tetracyclines. Common complaints associated with the drug are nausea, diarrhea and vomiting. About 3% of patients in clinical trials had to stop taking it because of stomach pain, skin rashes, lightheadedness or headache. Fewer than 1% experienced the more severe events, including the torn tendons, hallucinations and seizures...
...drug to the government for about $1.50 a dose, about one-third of the usual wholesale price. The Bush Administration has announced plans to spend $643 million increasing the nation?s drug stockpile, not only of Cipro, whose active ingredient is ciprofloxacin, but also of two other anthrax fighters, penicillin and doxycycline. Though they are much cheaper than Cipro, they are not as effective against genetically engineered anthrax...