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...mysteries that traditional genetics never could: for instance, why one member of a pair of identical twins can develop bipolar disorder or asthma even though the other is fine. Or why autism strikes boys four times as often as girls. Or why extreme changes in diet over a short period in Norrbotten could lead to extreme changes in longevity. In these cases, the genes may be the same, but their patterns of expression have clearly been tweaked. (See the best pictures...

Author: /time Magazine | Title: Why Your DNA Isn't Your Destiny | 1/6/2010 | See Source »

...ALSPAC has followed thousands of young people and their parents since before the kids were born, in 1991 and 1992. For the study, Golding and her staff recruited 14,024 pregnant mothers - 70% of all the women in the Bristol area who were pregnant during the 20-month recruitment period...

Author: /time Magazine | Title: Why Your DNA Isn't Your Destiny | 1/6/2010 | See Source »

...that of the 14,024 fathers in the study, 166 said they had started smoking before age 11 - just as their bodies were preparing to enter puberty. Boys are genetically isolated before puberty because they cannot form sperm. (Girls, by contrast, have their eggs from birth.) That makes the period around puberty fertile ground for epigenetic changes: If the environment is going to imprint epigenetic marks on genes in the Y chromosome, what better time to do it than when sperm is first starting to form...

Author: /time Magazine | Title: Why Your DNA Isn't Your Destiny | 1/6/2010 | See Source »

...book stores, he published Devil of a State, about his time in Brunei. He had begun writing the scathing send-up of British colonial life, which is an equally sarcastic take on local mores and hypocrisy, during the year doctors told him he had left to live - a period in which he wrote torrentially, hoping to leave a financial cushion for his widow-to-be. The glib novel is crazed with misanthropy, full of disloyal wives, derelict drunks, sexual assaults and riots - glimmers of what would come in the amoral, absurdist misadventures of Alex and his droogs in Clockwork...

Author: /time Magazine | Title: Anthony Burgess's Take on Brunei | 1/6/2010 | See Source »

...California has from its inception always limited marriage to the union of a man and a woman," wrote Charles Cooper, who served in the Reagan Administration's Justice Department with Olson, in his trial brief Dec. 7. "Indeed, until this decade, every State, nation and civilized society in every period of history had always limited marriage to opposite-sex relationships ... Contrary to Plaintiffs' contentions, the traditional definition of marriage does not reflect animus against gays and lesbians - in California or anywhere else." (See more about gay marriage...

Author: /time Magazine | Title: A Gay-Marriage Lawsuit Dares to Make Its Case | 1/5/2010 | See Source »

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