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...tumor in one’s adrenal glands, according to Kahn. “We thought, maybe the reason we’re not finding any brown fat is that we were not looking in the right place,” he said. Analyzing a combination of over 3000 PET and CT scans, the team found trace amounts of brown fat nestled under the muscles in the front of the neck. “This was actually a bothersome thing to the radiologists,” said Allison B. Goldfine, an associate professor at HMS and one of the paper?...
...foot of each volunteer into an ice bath while in the scanner. In a separate study, scientists at Maastricht University Medical Center in the Netherlands also saw upticks in brown-fat activity in subjects who had been chilling in a 16?C (61?F) room for two hours. (PET technicians have also long known that putting patients in warmer rooms tends to keep that bothersome extra activity from showing up on their images...
...sense, scientists have known this for years. While scanning patients with positron emission tomography (PET), an imaging technique often used on cancer patients to detect the spread of tumors, scientists have long noted the excess activity of brown-fat cells in their images. They just didn't realize what they were looking...
...Since PET picks up glucose-burning activity in cells, hot spots on PET scans of cancer patients generally indicate actively growing tumors. But after doing biopsies, doctors found that hot spots in the neck of most of their patients weren't cancerous at all. These turned out to be brown-fat deposits...
...forth to actually pinpoint whether the PET glucose-uptake areas corresponded to true brown-fat tissue, and I think we more or less proved the case," says Enerbäck, who found that those mystery cells in the neck expressed the same proteins as brown...