Word: pharmaceutica
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Sources: Archives of Pediatrics & Adolescent Medicine; New England Journal of Medicine; Jenssen Pharmaceutica...
...scientists are exploring an entire spectrum of what Dr. Steven Paul, vice president for central-nervous-system research at Eli Lilly, calls "Clozaril wannabes" that they hope will work as well without triggering agranulocytosis. One of the wannabes, risperidone (Risperdal), made by Belgium-based Janssen Pharmaceutica, entered the market in 1993, and four others are nearing approval by the fda, including Lilly's Zyprexa and Abbott Labs' Serlect. Meanwhile, further down the drug-development pipeline are a number of third-generation Clozaril cousins, some of which are specifically targeted at the little-known D3 and D4 receptors...
Researchers are working furiously to develop that something else. Janssen Pharmaceutica, a Belgium-based subsidiary of Johnson & Johnson, is in the lead with risperidone, a drug that so far appears to be safer than clozapine and works in the same way. Testing is incomplete, however, and the drug is at least 18 months away from the market. Abbott Labs, Eli Lilly and others are also developing successors to clozapine...
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