Word: pharmacologists
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Dates: during 1970-1979
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...theory is based largely on work with laboratory animals. At the University of Vermont College of Medicine, Pharmacologist Lester Soyka and Psychologist Justin Joffe have been administering methadone to male rats a few days before letting them mate with drug "clean" females. Among the adverse effects on the offspring: small litter size, low birth weights and excessive number of deaths among the newborn. Preliminary experiments with morphine, caffeine and the painkiller propoxyphene (Darvon) produced similar patterns...
...brain and spinal cord where such drugs as opium and morphine act. These and other recent discoveries open up the possibility of aiming artificial drugs at specific receptors, and perhaps duplicating the body's natural internal "drugs" that help keep normal people normal. Says Solomon Snyder, a psychiatrist and pharmacologist at Johns Hopkins University: "As a result of psychopharmacology, psychiatry has come from behind the other medical sciences to a position of leadership. We've got a whole new psychiatry...
Sharing the $15,000 prize were Dr. Hans Kosterlitz of the University of Aberdeen in Scotland, Pharmacologist John Hughes of the Imperial College of Science and Technology in London and Dr. Solomon Snyder of Baltimore's Johns Hopkins University...
...award for basic medical research was shared by Drs. K. Sune Bergström and Bengt Samuelsson, both of Stockholm's Karolinska Institute, and Pharmacologist John R. Vane of Britain's Wellcome Research Laboratories. The three men were honored for their pioneering work in identifying and isolating prostaglandins. First thought to be produced only by the prostate gland-hence the name-prostaglandins are in fact manufactured and found everywhere in the body. They are like hormones and appear to regulate a wide variety of basic life functions, from controlling the clotting of blood and secretion of gastric acid...
...James Whyte Black of London's University College, a pharmacologist as well as physician, worked with chemists at Smith Kline & French Laboratories to find what are awkwardly called H2-receptor blockers. After testing over 700 compounds, they finally hit upon cimetidine. At present, their discovery has been approved for up to only eight-weeks' use by duodenal-ulcer patients and by victims of a few other diseases causing excessive acid secretion, like gastrinoma (tumors of the pancreas). Under the brand name Tagamet, the new drug should be available (on prescription only) by Labor Day. Cost of a four...