Word: pharmacologists
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Dates: during 1990-1999
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...Right, pronounces Ohman. Which drug? They stumble with answers until Ohman says it's Esmolol. That surprises one of the young physicians. Esmolol, he notes, could cost as much as $200 a day, while alternatives can be had for $1.50 a pill. Ohman casts an eye toward the clinical pharmacologist accompanying the group. "How am I going to battle him down?" he asks his colleague...
...right answer eventually emerges from their Socratic discourse: if the patient starts to have problems, Esmolol can be stopped and, within minutes, so will its chemical effect. Cheaper drugs can't be turned off so quickly. "It will cost more, but that's O.K.," says Gary Dunham, the pharmacologist who is sharing rounds with Ohman. If the woman gets in trouble with one of the cheaper drugs, he says, her health-care costs will soar. Dunham lectures again in the language of cost-based pharmacotherapy: "It's the most effective drug at the least societal cost...
Still, the German experience suggests that St. John's wort is relatively harmless. "Millions of people have taken, or are now taking, hypericum," observes Jerry Cott, a Maryland-based pharmacologist, "and none of the side effects reported have been anything like those we've seen with drugs like Prozac. That's kind of exciting." Indeed, just as aspirin (whose active ingredient was first isolated from the bark of the willow tree) has spurred the development of a new generation of anti-inflammatories, so hypericum may eventually stimulate the creation of safer, more powerful, antidepressant drugs...
...What they had found, Malbon told reporters last week, was an enzyme that acts as the master switch for breast cancer, a disease that kills 44,000 women in the U.S. each year. "This gives us a new diagnostic tool and a new therapeutic strategy," maintained Malbon, a pharmacologist at the State University of New York at Stony Brook...
...girls rarely seem to have either the chance or the inclination to get plugged in. Just ask Ralph Howell, a New Jersey pharmacologist, who got a Sega game player for his daughter Emily three years ago, when she was six. Emily loved the rollicking Sonic the Hedgehog but turned up her nose at a race-car program and one based on the hit flick Jurassic Park. "Anytime I brought home another game, she just wasn't interested," Howell says. He finally quit shopping...