Word: phases
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...information on the topic of global warming. Over 19% of searches on the term resulted in visits to Globalwarming.org, a site sponsored by the conservative Competitive Enterprise Institute, while 14% of global warming searches resulted in visits to Wikipedia.org, reinforcing the notion that we're still in the phase of learning more about the issue...
...researchers conducted Phase I trials at Buck and at the Cancer Research Network in Plantation, Fla. Their 21 participants had stage IV metastatic breast cancer, which had continued to progress despite an average of four rounds of standard treatment, including chemo and hormone therapy. The patients took 12 g a day of Ban Zhi Lian, a dose that's three times more concentrated than the amount found in a cup of brewed tea. After about a year, 25% of the patients saw stabilization in their disease for 90 days, and 19% for 180 days. The experimenters say BZL101 works...
...Tagliaferri and Cohen left Buck to establish Bionovo, where they began Phase II trials of BZL101 in April 2006, expanding their studies to 10 hospitals and breast cancer centers, including the University of Chicago Medical Center, Duke University Medical Center and the M.D. Anderson Cancer Center in Houston. Bionovo expects the second phase of trials to conclude by early...
...herbal therapy and a lot of people take herbs, research in herbal therapy is difficult because you're dealing with a mixture of compounds," says Tripathy, who is now a clinical professor of internal medicine at the University of Texas Southwestern Medical Center in Dallas. During the research phase, Tripathy says, scientists often attempt to isolate one particular molecule or compound from the herbal extract - and the anticancer activity is lost. "There are herbal extracts in which the anticancer activity is actually due to the synergy between many of the compounds contained in that extract," he says...
Tripathy also says that companies like Bionovo have a tough time getting funding either from the private sector or from pharmaceutical companies: "In the absence of controlled clinical trials, people are skeptical and say 'There's no evidence this works,'" he says. Bionovo, which expects to begin Phase III trials in 2009, hopes to upset this way of thinking. And, says Tagliaferri, the company is studying about two dozen other Chinese herbs with anticancer potential...