Word: phenylketonuria
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Dates: during 1980-1989
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...ahead actually was granted in 1974, but was stayed pending investigation of charges that aspartame might cause brain damage and that the animal studies submitted by manufacturer G.D. Searle were flawed. The charges were dismissed. However, the FDA says that aspartame should be avoided by victims of phenylketonuria, a condition characterized by the inability to metabolize the amino acid phenylalanine, that can result in mental retardation. Aspartame contains phenylalanine and will carry a warning on the label...
While the experiment offers the possibility that by changing the genetic material in the human egg, doctors may one day be able to eliminate a host of inherited diseases-including hemophilia, Tay-Sachs disease and phenylketonuria, a metabolic disorder that may result in brain damage-many basic questions must first be answered. For example, will the transplanted genes actually work as they are supposed to or will they be modified or inactivated by the animal's own genetic machinery? Will the foreign genes free-float in the cells or will they latch on to the other genes arranged along...