Word: phi
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Dates: during 1960-1969
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...with Impurities. Taking natural DNA from a simple virus called Phi X 174 (which consists only of a DNA molecule surrounded by a protein sheath), they added it to the brew as a template, or blueprint, to guide the assembly of the synthetic molecule. Under the influence of the DNA polymerase enzyme, the four basic nucleotides aligned themselves in codelike combinations alongside the natural DNA molecule. Eventually they formed a strand consisting of about 6,000 nucleotide units that was a mirror image of the corresponding strand in the natural molecule. Then, using their mirror-image molecule as a template...
Sinsheimer placed the synthetic DNA molecules into laboratory dishes filled with Phi X's natural victim, E. coli bacteria, which are common intestinal microbes. Invading the E. coli cells, the DNA molecules directed them to produce hundreds of Phi X viruses, each complete with its protein coat. Eventually the invaded cells ruptured under their burden of viruses, killing the bacteria and releasing the viruses to infect other cells. The progeny of the synthetic DNA molecules were not only biologically active but could not be distinguished from natural Phi X viruses...
...Phi Beta Kappa has elected its Senior Sixteen. They are: Donald M. Berwick of Winthrop House and Moodis, Conn.; James F. Coakley of Leverett and Arlington, Va.; Bruce C. Dieffenbach of Winthrop and Washington, D.C.; Stephen W. DeYoung of Adams and Rochester, N.Y.; Richard S. Ellis of Winthrop and Dorchester; and also Irwin Gaines of Lowell and New Rochelle, N.Y.; Ira G. Greenberg of Dunster and Miami, Fla.; Walter Jaros of Adams and Great Neck, N.Y.; and Michio Kaku of Leverett and Palo Alto, Calif...
Butcher's financial talent dovetails with Seabrook's knack for curing sick companies. A Phi Beta Kappa graduate ('39) of Princeton, Seabrook first rescued his own family company, Seabrook Farms, from a disastrous slump. In 1959, when his father, now dead, sold control of the frozen-food firm, Seabrook quit as president and joined Butcher. He became president of I.U. in 1965, and of General Waterworks last year. Often his doctoring of acquisitions involves nothing more startling than sending in a financial expert to bail out a sales-minded boss. "A lot of companies are mismanaged...
Female Fellini. Aline Saarinen, nee Bernstein, keeps her work bright, light and informative, without ever making the highbrow seem high-blown. A Phi Beta Kappa from Vassar, whose girlhood goal was to be "intelluptuous," she got a job on Art News "because I could spell Pollaiuolo,"* rose to managing editor in 1944, a year later joined the New York Times as an art critic. While on an assignment in 1952, she interviewed and later married Finnish-born Architect Eero Saarinen (it was her second marriage). After his death eight years later, she appeared on a 1962 CBS special on Lincoln...