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...scientists at Northwestern University were the first to show why the brain's "memory function" fails in the face of an insulin shortage. The group's prior research had already pinpointed the culprit: toxic proteins called amyloid beta-derived diffusible ligands (ADDLs, for short), which are known to pile up in the brains of people with Alzheimer's. Scientists also knew that Alzheimer's patients' brains have lower levels of insulin and are insulin resistant. But what the Northwestern team discovered is the molecular mechanism behind that resistance: when ADDLs bind to neurons at synapses, they obliterate the receptors that...

Author: /time Magazine | Title: Is Alzheimer's a Form of Diabetes? | 10/18/2007 | See Source »

...issues of the New York Times and Fifteen Minutes. Even so, she joins fellow designer Alexandra M. Hays ’09 for a trip to The Garment District later that afternoon, where both begin picking through the massive “dollar-fifty a pound” clothing pile. Mid-treasure hunt, Morton’s model calls for details. “It’s going to be made of newspaper, just to warn you,” Morton cautions with a grin. “It’s a conceptual outfit...

Author: By Erin C. Yu, CONTRIBUTING WRITER | Title: Thea S. Morton '06-'08 | 10/17/2007 | See Source »

...there is something strange about all this heat and division. As the dust rises and the opinions, concurrences and dissents pile up, the court turns its attention to ever smaller cases related to ever narrower points of law. There is, it seems, an inverse relationship between the passions expressed in judicial writings and the import of the cases that inspire them. In the midst of these battles, no one seems to have noticed that the stakes have diminished. This trend--a steady shrinking of the judicial role in public policy and a handing over of issues to the states...

Author: /time Magazine | Title: The Incredibly Shrinking Court | 10/11/2007 | See Source »

...heart attack and an 8% chance of dying within 30 days; similar patients who did not get a transfusion had an 8% chance of a cardiac event and a 3% chance of death. Stamler believes that without NO, red blood cells are not dilating tiny vessels properly and instead pile up in the narrow passageways, blocking flow and damaging the very heart tissue the blood was transfused to help...

Author: /time Magazine | Title: The Problem with Transfusions | 10/11/2007 | See Source »

...attack and an 8% chance of dying within 30 days; similar patients who do not get transfused have an 8% chance of a cardiac event and a 3% chance of death. Stamler hypothesizes that without NO, red blood cells cannot drill their way into tiny blood vessels; rather, they pile up in narrow passageways, blocking blood flow instead of increasing it and hampering the heart...

Author: /time Magazine | Title: Why Banked Blood Goes Bad | 10/8/2007 | See Source »

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