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...charged issue of abortion as one of his first acts as president is sure to delight conservatives, but it raises questions about his repeated promise to unite Democrats and Republicans. Anti-abortion activists hope that he will go even further by putting new restrictions on RU-486, the abortion pill authorized last year by the Food and Drug Administration. Their ultimate goal is for Bush to appoint new Supreme Court Justices who will overturn Roe v. Wade...
...Thompson has been quieter than Ashcroft about his opposition to abortion. That reticence continues today; if Thompson is looking for a fight from his Senate panel, he's doing it quietly. When asked during his hearings whether he would seek to repeal FDA approval of the controversial "abortion pill," RU-486, Thompson replied, "I don't intend to roll back anything unless it's proven to be unsafe." And although the FDA's approval is dependent upon positive results in extensive safety and efficacy tests, Thompson indicated he did not feel the case was necessarily closed to further analysis...
...substantial portion of drugs taken orally, in pill or liquid form, is lost to digestive processes and removed by the liver, and what remains can irritate the intestinal tract. Enter transdermal patches. First designed to treat motion sickness, they slowly deliver drugs through the skin from a reservoir within the patch, and are being used increasingly to treat hypertension, angina and other disorders. So far, the patches are limited to carrying small-molecule drugs that can diffuse through the skin. But several teams are experimenting with electrical or ultrasonic devices that can also push larger-molecule drugs through the skin...
About 30% of patients who begin therapy with a combination of antiviral drugs have to stop, either because their bodies cannot tolerate the toxic side effects or because they cannot keep up with the grueling regimen of strictly scheduled pill popping. An additional 30% to 50% are currently in salvage therapy, which is what AIDS specialists call the last-ditch potions of drug cocktails given to patients who have become resistant, one by one, to every class of antiviral on the market. "We have, by treating lots of individuals relatively successfully for varying periods of time, accumulated a new target...
ABORTION OPTION Last year when the FDA approved RU-486, it said the abortion pill should be taken with a second drug, misoprostol, to help expel the fetus. That didn't stop misoprostol's controversy-shy manufacturer, Searle, from warning doctors that the drug could harm pregnant women. Well, it doesn't seem to, according to a review of 200 studies that found misoprostol safe for a number of obstetrical uses, including labor induction and medical abortion...