Word: pincus
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Dates: during 1960-1969
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...Boston Gynecologist John Rock, despite his Roman Catholic faith, put his name to a birth-control petition nearly 40 years ago. This modest act was dictated by conscience rather than defiance. With Dr. Gregory Pincus and Dr. M. C. Chang, Rock went on to develop the Pill, the first really effective contraceptive device. As Pope Paul VIs encyclical made clear last summer, the Catholic hierarchy is not yet prepared to abandon a position that it has maintained for 1,770 years. When it does, John Rock's courage and example will have played a significant part in this profound...
Died. Gregory Goodwin Pincus, 64, research director of the Worcester Foundation for Experimental Biology and a brain father of birth control pills; of myeloid metaplasia, a blood disease; in Boston. A brilliant biologist, Pincus first won national attention in 1939 by inducing a "fatherless" mammalian birth (a lab-fertilized rabbit egg); then in the 1950s, with Harvard Gynecologist John Rock, successfully tested an ovulation depressant called progestin, which came on the market in 1960 as Enovid. At his death, Pincus was testing yet another idea: a "morning after" pill, which keeps fertilized eggs from settling in the womb...
...Pincus Pills." Probably no single name will be forever linked with the pills, as is Jenner's with vaccination. The search for medically useful knowledge nowadays goes along parallel lines at many places, often with a team working at each center. But Physiologist Gregory Pincus of the Worcester Foundation for Experimental Biology and Gynecologist John Rock of Harvard University rate high among the pioneers of oral contraception. It was at Harvard, too, that Dr. Fuller Albright noted in the mid-1940s that an excess of estrogen* in the bloodstream soon after the end of menstruation somehow prevented ovulation...
...patients complain of too much "breakthrough bleeding" in mid-cycle. Analysis showed that the purified drug contained no detectable estrogen. Apparently estrogen, even in the most minute quantity, prevented some side effects, including unwanted bleeding. So when Chicago's G. D. Searle & Co., which had worked closely with Pincus and Rock, began making "the Pincus pills" as Enovid in 1957, the formulation contained 66 parts progestin to one part estrogen. The progestin dose has been reduced by as much as 90% in Searle's newest pills, Ovulen, but the combination principle is the same...
Neuman and Pincus have spent the past year editing 40 hours of film clips. Recently they returned to Natchez to film reactions to the murder of civil rights leader Wharlest Jackson, February...