Word: pioneer
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...mutual-fund company has begun offering a hundred new ways for you to invest your money. He popularized the notion of risk management, one of the most important ideas in modern finance. He didn't come up with the notion (credit academia), but more than anyone else he helped pioneer a new kind of risk-aware investing that offered a first glimpse of a world of high-wire, high-tech finance. His legacy has touched every American with a home loan, a credit card or a checkbook. And it has not only made consolidators like McColl and Weill possible...
Another candidate, Jamie C. Gorelick '72--a "pioneer" in Harvard's co-education story, having lived in Quincy House in its first year of experimental co-ed housing--says the University has done well to integrate women into its most essential decision-making processes...
Fortunately, with Lidie, Smiley proves once again that she can jump through genres with the blink of a metaphorical eye and leaves the `repetitive subject matter' label with the likes of John Grisham and Danielle Steele. She takes the astoundingly courageous story of one pioneer woman, mixes it with a potentially-dry `olde-tyme' writing style and comes up with a tale that takes a few pages to get into, but that takes great effort...
...have any sense of being a pioneer, asI was at the Law School," she said. "I follow inthe steps of some very able, qualified women...
Vertex, founded by a Harvard graduate in 1989, is a pioneer in "structure-based drug design." In theory, the idea is plausible enough: if one knows the precise three-dimensional structure of an enzyme target, one can use a computer to design a perfectly complementary "small molecule drug" to jam into the enzyme and disable it, just as a locksmith can build a key from scratch to open a lock...