Word: piot
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...Research Unit in Durban, South Africa, has worked with all five, and is hopeful that they will prove effective and make an impact on the disease. Because these latest microbicides are reformulated ARVs, however, the problem of the virus becoming resistant to them is a potential drawback. Dr. Peter Piot, of UNAIDS, suggests basing microbicides only on the drugs that do not make it through the pharmaceutical pipeline - many are rejected because they don't maintain high enough levels in the blood to treat an HIV infection, but could be sufficiently powerful to prevent transmission. But Zeda Rosenberg...
...being tested in groups at highest risk of transmitting the virus - commercial sex workers and gay men. "What you want is a high level of ARV in the blood and body secretions, so that when you are exposed to HIV, the ARV will kill the virus," explains Dr. Peter Piot, director of UNAIDS. "Because at infection, the number of virus particles is very, very small, so you can inhibit or kill them before they penetrate cells or just at the early phases of infection...
...Piot, however, notes that if PrEPs prove effective, they will create a number of thorny ethical issues: How will use of the drug be monitored? Could it become a "party" drug or a Viagra-like crutch that people erroneously believe will provide them with absolute protection? "We'll need a lot of behavioral research, which I think should be initiated as soon as possible," he says. "Particularly when it looks like PrEP will become a reality." Resistance is a key issue with PrEP as well, and if effective PrEP drugs are used widely, the problem of resistant HIV expands exponentially...
...viruses have made this leap--notably jungle yellow fever virus--and, he notes, the greens often live in close association with people and frequently bite them. How the disease might have traveled from Africa to the U.S. and Haiti is anybody's guess. One "intriguing" clue, says Dr. Peter Piot of the Institute for Tropical Medicine in Antwerp, Belgium, is that several thousand Haitians lived in Kinshasa, Zaďre, from the early 1960s to the mid-'70s, and most of them, he says, have since moved to North America and Europe. As another researcher put it, the virus "didn...
...Piot added that one aim of the first round of conferences was to encourage large companies to be leaders...