Word: pitressin
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Dates: during 1946-1946
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...John Quintin Griffith Jr., and colleagues at Penn's Medical School clinic, discovered several years ago that the blood serum of some patients with high blood pressure contained a pituitary hormone which slows up the secretion of urine. A synthetic preparation of the hormone, called pitressin, was found to have a peculiar property: injected into a patient, it reduces urine secretion at first, but after a few days increases...
...Griffith's explanation: pitressin may stimulate the body to produce an antihormone which neutralizes the hormone responsible for urine suppression and high blood pressure. As a test, he gave pitressin injections to 63 patients for several months. Result: half his patients improved; in some, blood pressure dropped to normal, stayed normal after injections stopped...
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