Word: pkr
(lookup in dictionary)
(lookup stats)
Dates: during 2010-2010
Sort By: most recent first
(reverse)
...researchers are optimistic that their discovery of this additional function of PKR could lead to a better understanding of metabolic disorders and ultimately, to treatments...
...PKR, after being activated by lipids and other nutrients, participates in the clustering of other molecules—creating a complex the researchers termed “metaflammasome”—which in turn leads to chronic inflammation...
After measuring the enzyme levels in the liver and fatty tissues from both lean and obese mice, they found that levels of PKR activation were strongly correlated with the amount of fatty tissue in the mice...
...study also shows that PKR directly interferes with normal insulin function in a way that could lead to the onset of type 2 diabetes...
...Understanding the specific mechanism of how lipids activate PKR could be the next exciting avenue of discovery,” Mitchell said...