Word: plasminogen
(lookup in dictionary)
(lookup stats)
Dates: all
Sort By: most recent first
(reverse)
...such a crazy idea that none of the researchers in Folkman's lab wanted anything to do with it. Finally one of them, Dr. Michael O'Reilly, agreed to take on the project. Together he and Folkman eventually determined that various segments of a naturally occurring protein called plasminogen seemed to do the trick. They called the collection of molecular fragments angiostatin and found that each version of the compound differed slightly in its ability to stop a tumor from growing...
Endostatin is part of the molecule collagen 18, while angiostatin is part of plasminogen, a blood clotting agent...
...results with TPA, or tissue plasminogen activator, have been nothing short of astonishing. The drug dissolves blood-vessel clots that block blood flow to the brain. "This is a particularly exciting time," says Dr. Mark Dyken, professor emeritus of neurology at Indiana University and the editor of the research journal Stroke. "In the past, most doctors thought of a stroke as the end, and that nothing could be done...
...most terrifying. Suddenly, your arm goes numb. You can't speak. Half your body becomes useless. Until recently, doctors could do little more than watch as their stroke patients either recovered on their own or became permanently paralyzed. Then researchers determined that a drug called tissue plasminogen activator, or TPA, which has been used for years to treat heart attacks, can also alter the course of a stroke. But many physicians wouldn't try the new treatment because there is also a chance that it can make a stroke patient's condition worse. That reluctance may begin to fade...
...drug already used to treat heart attacks also reduces the damage caused by strokes, a European study shows. The medicine, TPA -- tissue plasminogen activator -- enabled stroke victims to live healthier lives, but did not reduce their death rate, according to researchers at the University of Heidelberg in Germany. "For stroke victims this news is important because just a little more ability goes a long way," saysTIME science writer Christine Gorman. "If you have 10 percent more ability in your left hand -- it's amazing how important that is to someone who has had a stroke and survived." Approximately...