Word: playfulness
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...significant breakthrough, the team successfully identified that a particular gene sequence was associated with differences in telomere length between individuals. What's more, the sequence was clustered near a gene called TERC, which is already known to play a role in the production of an enzyme called telomerase. Telomerase repairs telomeres when they shorten. "That was very exciting for us," says Nilesh Samani, a cardiologist at the University of Leicester who co-led the research, which was published last week in Nature Genetics. "It gave us great confidence that we identified genetic variants on a pathway we already know...
...Samani also says the telomere research offered no quick fixes and that telomere-based treatments were still a long way off. The reason for this is that telomeres - while potentially lowering the risk of heart disease - play a role in the development of cancer cells. "We all probably develop cancer cells that don't get past a few replications because of the effect of normal telomere shortening. If you make cells immortal by allowing them to replenish their telomeres, you may raise the risk of many nasty cancers considerably...
...Eighteen years later, Nair cast him in The Namesake, and he rendered a quietly commanding performance. Khan plays Ashoke Ganguli, an Indian immigrant to the U.S. struggling to connect with his Westernized son. Khan had never been to the U.S. before then, so to play Ashoke he called on an earlier trip to Canada, where he had noticed the many middle-aged immigrants working in shops. "Something stayed in my mind," he says. "A strange sadness set in them. A rhythm that middle-aged people have." Nair says he was true to the quietness of the character, but used...
...drugs. Netting $134 billion globally in 2008, these therapies for treating chronic diseases--about half of which are oncology drugs--represent one of the fastest-growing segments of the health care market. AmerisourceBergen's revenue in the sector topped $16 billion last fiscal year. "If Cardinal is going to play, they have to move now," says Sanford C. Bernstein & Co. analyst Helene Wolk, who is bearish on Cardinal. "And they're going to have to buy, not build, to get to scale as quickly as possible...
DAVE MATTHEWS, musician, responding to rumors that disgraced presidential contender John Edwards had once talked with his mistress Rielle Hunter about getting the singer's band to play at their wedding...