Word: pleconaril
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Another antiviral drug, called pleconaril, had the rug pulled out from under it last March when the U.S. Food and Drug Administration declined to approve it, citing concerns that pleconaril might interfere with the effectiveness of oral contraceptives and other drugs. To combat that problem, Viropharma, the biotech company that developed pleconaril, decided to reformulate the pill, turning it into a nasal spray, thereby lowering its dose and the chance that it might interfere with other drugs. Viropharma is now looking for another pharmaceutical company to help defray the costs of testing the new formula...
COLD WAR Are scientists closing in on a cure for the common cold? Researchers report that besides alleviating a runny nose and achy muscles, a drug called pleconaril cuts the duration of a cold by one day. Though that may not sound very dramatic, the way pleconaril works is. Other remedies merely fight symptoms; this drug attacks the cold virus itself, destroying its ability to reproduce. FDA approval is not expected until after this year's cold and flu season...
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