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Other recent studies have also shown the power of environment over gene expression. For instance, fruit flies exposed to a drug called geldanamycin show unusual outgrowths on their eyes that can last through at least 13 generations of offspring even though no change in DNA has occurred (and generations 2 through 13 were not directly exposed to the drug). Similarly, according to a paper published last year in the Quarterly Review of Biology by Eva Jablonka (an epigenetic pioneer) and Gal Raz of Tel Aviv University, roundworms fed with a kind of bacteria can feature a small, dumpy appearance...

Author: /time Magazine | Title: Why Your DNA Isn't Your Destiny | 1/6/2010 | See Source »

Exploring Epigenetic Potential How can we harness the power of epigenetics for good? In 2008 the National Institutes of Health (NIH) announced it would pour $190 million into a multilab, nationwide initiative to understand "how and when epigenetic processes control genes." Dr. Elias Zerhouni, who directed the NIH when it awarded the grant, said at the time - in a phrase slightly too dry for its import - that epigenetics had become "a central issue in biology." (See TIME's health and medicine covers...

Author: /time Magazine | Title: Why Your DNA Isn't Your Destiny | 1/6/2010 | See Source »

...billion to map them all. The human epigenome contains an as yet unknowable number of patterns of epigenetic marks, a number so big that Ecker won't even speculate on it. The number is certainly in the millions. A full epigenome map will require major advances in computing power. When completed, the Human Epigenome Project (already under way in Europe) will make the Human Genome Project look like homework that 15th century kids did with an abacus...

Author: /time Magazine | Title: Why Your DNA Isn't Your Destiny | 1/6/2010 | See Source »

...south and the growing presence of al-Qaeda in the Arabian Peninsula (AQAP) all threaten the state, while a water crisis and relentless poverty threaten the people. Resources have become even more scarce with constant waves of refugees from Somalia, Ethiopia and Eritrea. Meanwhile, the government, which has little power outside of the cities, is disorganized and weak. The ministries and the parliament technically have some power, but almost all leaders are connected - if not actually related - to the President. Nepotism and corruption are an everyday occurrence, and the television and print media are overwhelmingly state-run. (See a video...

Author: /time Magazine | Title: In Yemen's Capital, Fearful Talk of War with al-Qaeda | 1/6/2010 | See Source »

...majesty of the mosque, impoverished Yemenis languish in a dusty beige slum across the street. Yemen's urban poor often live in makeshift homes built with found items like tarp, tires and rocks. There is never running water, and electricity comes from wires that are jerry-rigged to government power lines. "Inside [the mosque] you see you are in paradise," says Khaled al-Hilaly from his nearby office at the Yemen Times, one of the few newspapers not funded by the government. "Then you go out, and then you are in hell." (See the top 10 news stories...

Author: /time Magazine | Title: In Yemen's Capital, Fearful Talk of War with al-Qaeda | 1/6/2010 | See Source »

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