Word: ppl
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Dates: during 2000-2009
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E.ON isn't openly in talks with anyone yet, but speculation centers on companies that are located near LG&E. J.P. Morgan Chase utility analyst Pierre Stiennon says to look for a deal with Cinergy, based in Cincinnati, Ohio; Allegheny Energy in Hagerstown, Md.; or PPL of Allentown, Pa. All three companies produce and sell power on the wholesale market and also serve a large base of regulated retail customers. Hartmann is known as a careful shopper. When he explored a U.S. acquisition as CEO of Veba, the man on the other side of the table was Enron's Jeff...
...solution may be on the horizon. Last week two research teams said they had removed the pig gene responsible for the most severe form of rejection. Not only that. Both teams--one from PPL Therapeutics, which in 1996 helped make Dolly the sheep, the first mammal cloned from an adult animal, and the other from the University of Missouri-Columbia and Immerge BioTherapeutics, of Charlestown, Mass.--then cloned their little pigs, producing five and four piglets, respectively...
Finally, cloning often produces animals that are deformed or die young; they may age prematurely as well. Just last week researchers at Scotland's Roslin Institute, PPL's partner in the Dolly experiment, reported that their famous ewe has come down with arthritis at age 5 1/2--a condition that may be related to her cloning...
...hope for increasing the nation's too-small supply of transplantable organs came Thursday as researchers publicized the completion of a significant step forward in developing pig organs for use in human patients. The announcements came from scientists on two different teams, one from PPL Therapeutics Inc. in Blacksburg, Virginia, and the other representing a joint effort by the University of Missouri and Immerge BioTherapeutics Inc., based in Charlestown, Massachusetts. Both groups reported they have produced pigs that lack GGTA1, one of two genes that cause the human body to reject organs harvested from swine. Experts, while careful to note...
Despite this recent success, PPL is not likely to be setting up its organ shop anytime soon. Knocking out the key sugar gene solves only the problem of short-term rejection. Long-term rejection, caused by blood coagulating around the new organ, requires that researchers re-engineer an entirely different set of genes that code for anticoagulants. But even this would not be a perfect solution, and recipients of pig organs would probably still have to take the same rainbow of antirejection drugs recipients of human organs must now endure...