Word: pregnant
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Dates: during 2000-2009
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...drug, metoclopramide, is not approved by the U.S. Food and Drug Administration (FDA) for use in pregnant women, but it is dispensed widely in Europe and other places to treat morning sickness. In the new study, the largest one of maternal metoclopramide use to date, involving nearly 3,500 babies born between 1998 and 2007 in a region in southern Israel, the rate of congenital birth defects in babies born to mothers who used the anti-nausea drug was about the same as that in babies whose mothers had not (5.3% vs. 4.9%). What's more, the length of time...
...treatment, since most expecting mothers and their doctors aren't keen on exposing a still developing fetus to medications. Now, researchers from Israel and Canada report in the New England Journal of Medicine that a commonly prescribed heartburn drug, which also has anti-nausea properties, may be used in pregnant women without causing harm to babies. (See safety issues about taking pills during pregnancy...
...prescribed metoclopramide more liberally, and Dr. Gideon Koren, director of the University of Toronto's Motherisk Program for the study of antenatal drugs, saw an opportunity to address divided concerns about the medication. Collaborating with a large HMO in Israel, he and his multinational colleagues studied metoclopramide use in pregnant women and its association with babies' health outcomes - specifically, birth defects, premature birth, low birth weight, Apgar score (which provides an immediate measure of a baby's physical condition at birth) and infant death...
...Autopsy reports and forensic investigations have confirmed that Aasiya and Nilofar, who was pregnant, were both raped, but authorities have not yet confirmed that either woman was murdered. A special police team has been assigned to the investigation. So far, no charges have been made, but chief minister of Indian-administered-Kashmir Omar Abdullah has said the government is committed to finding the perpetrators of the violent crime. "Nilofar and Aasiya were like my sisters and I, as brother, feel the pain of the tragedy that has befallen the victim family," Omar said. He pledged not to rest till...
That's why the FDA is moving toward ditching these broadly defined categories in favor of a more narrative, evidence-based summary of what's known about an individual drug and its effect on pregnant and nursing women. "People are very uncomfortable with shades of gray," Feibus says, "and pregnancy is all gray." Of course, Second Wavers are hoping that won't always be the case...