Word: premarin
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...research reveals the pros and cons of estrogen, the therapy's popularity has flowed and ebbed like some sort of national hormonal cycle. Wilson's book did wonders for the sale of Premarin (a form of estrogen made from -- and named for -- a pregnant mare's urine). But estrogen use plummeted after 1975, when studies revealed that women taking the hormone had up to a 14-fold increased risk of uterine cancer. Reports of a 30% increased risk of breast cancer scared away many others...
...normal and has been experienced since time immemorial?" Well, yes -- Japanese women, for example, don't even have a word for "hot flash" -- but never mind. Menopause is a swamp of pathology, in Sheehy's view, curable with a positive attitude and, in appropriate cases, a lifetime supply of Premarin...
...invariably paid much less at wholesale for the generic drugs, they often marked up the prices of generics much more sharply than those of name brands. In some cases consumers paid even more for generics than for name brands. For example, generic conjugated estrogens cost less than the equivalent Premarin brand only 40% of the time...
...side effects from female sex hormones. Figuring that heart disease sufferers would not mind such symptoms if they also developed one more aspect of femininity - relative immunity from heart attacks until late in life - Chicago's Dr. Jeremiah Stamler and fellow researchers treated a group of patients with Premarin, a combination of estrogenic hormones...
Without such treatment, Dr. Stamler told a symposium at Philadelphia's Hahnemann Medical College, 17% of men die within five years after a single, uncomplicated heart attack; 71% die after a more serious attack or a succession of attacks. After five years on Premarin, the corresponding death rates were 7% and 27%. But dosage is critical. Dr. Stamler warned against giving Premarin within three months after a heart attack, advocated building up in stages after that from 1.25 mg. to 5 mg. a day. Los Angeles' Dr. Jessie Marmorston reported that she got good results (TIME, June...