Word: premarin
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Dates: during 1962-1962
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...side effects from female sex hormones. Figuring that heart disease sufferers would not mind such symptoms if they also developed one more aspect of femininity - relative immunity from heart attacks until late in life - Chicago's Dr. Jeremiah Stamler and fellow researchers treated a group of patients with Premarin, a combination of estrogenic hormones...
Without such treatment, Dr. Stamler told a symposium at Philadelphia's Hahnemann Medical College, 17% of men die within five years after a single, uncomplicated heart attack; 71% die after a more serious attack or a succession of attacks. After five years on Premarin, the corresponding death rates were 7% and 27%. But dosage is critical. Dr. Stamler warned against giving Premarin within three months after a heart attack, advocated building up in stages after that from 1.25 mg. to 5 mg. a day. Los Angeles' Dr. Jessie Marmorston reported that she got good results (TIME, June...