Word: prempro
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Dates: during 2000-2009
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There was widespread shock and dismay last year when researchers reported that a popular combination of female hormones called Prempro, taken for more than a couple of years, increases a woman's risk of developing heart disease and breast cancer. The news seemed to sound the death knell for long-term hormone-replacement therapy (HRT). Yet even at the time, scientists recognized that there was a chance for a reprieve: the estrogen-progestin mix might still delay or even prevent various kinds of dementia, including Alzheimer's disease. To find out, researchers began a careful analysis of a subset...
...year-old woman who started hormone-replacement therapy last year because I was in menopausal agony. The hot flashes every 20 minutes, all day, night sweats and the feeling that nothing was smooth prompted me to see my doctor and begin HRT. I take half the recommended dose of Prempro, and I get along wonderfully. I am concerned about what the Women's Health Initiative study has shown, but for now I will keep taking my little half a pill each day. SARAH J. HEARN Kinsley, Kans...
...much for the major conclusions. Now for the caveats and complications. The WHI study looked at the most popular brand of estrogen and progestin, which is called Prempro and is made by Wyeth. Technically speaking, the WHI findings do not apply to other products. Some doctors have speculated that lower-dose hormones or estrogen-progestin patches and creams might somehow avoid some of the risks associated with Prempro. That has yet to be proved. Even so-called natural hormones (those derived from plants) aren't necessarily risk free. For one thing, they haven't been as carefully tested as Prempro...
...dying. "I was aching all over and crying all the time," she recalls. "At one point I was cutting a man's hair when, out of the blue, I had to fight back tears." Fulbright tried alternative remedies, like yam creams, but relief came only when she tried Prempro four months ago. "It was like a miracle," Fulbright says. "I was back to my normal self...