Word: prepped
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Dates: during 2000-2009
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...Even more tantalizing than the microbicides is the idea of taking a pill before intercourse or other high-risk behavior, and thereby becoming protected from HIV. Drugs for pre-exposure prophylaxis (PrEP) were born from the success of programs that prevent mother-to- child transmission; since ARVs given to women pre- and post- delivery are effective in reducing the transmission of HIV to the child, some experts believe that using ARVs before exposure to HIV may have the same effect in protecting partners. Five trials, all involving two compounds, Tenofovir or Truvada, are now underway in Thailand, Botswana, Peru, West...
...Piot, however, notes that if PrEPs prove effective, they will create a number of thorny ethical issues: How will use of the drug be monitored? Could it become a "party" drug or a Viagra-like crutch that people erroneously believe will provide them with absolute protection? "We'll need a lot of behavioral research, which I think should be initiated as soon as possible," he says. "Particularly when it looks like PrEP will become a reality." Resistance is a key issue with PrEP as well, and if effective PrEP drugs are used widely, the problem of resistant HIV expands exponentially...
...study where she writes her novels; it's airy and messy - she and her boyfriend moved in last August, but there are still boxes on the floor. So far, you would never know that you were visiting the home of the Faulkner of awkwardness. Sittenfeld's first novel, Prep, was the sleeper hit of 2005. It tells the bittersweet, perfectly observed story of Lee, a quiet Midwestern girl who tries, with decidedly mixed results, to fit in at a breathtakingly preppy Eastern private school. To the surprise of many, not least its publisher and its author, Prep spent nine weeks...
...Incredibly Close) has got a lot of attention both popular and critical, and he's only 29. A somewhat partisan sampling would also include Colson Whitehead (The Intuitionist), 36; Edwidge Danticat (Breath, Eyes, Memory), 37; Dave Eggers (You Shall Know Our Velocity), 36; Arthur Phillips (Prague), 37; Curtis Sittenfeld (Prep), 30; Myla Goldberg (Bee Season), 34; Nicole Krauss (The History of Love), 31; and Gary Shteyngart (Absurdistan), 33. If we open our borders to the Brits, we also get Zadie Smith (On Beauty), who at 30 is probably her generation's consensus No. 1 seed, as well as Monica...
...narrative roots of genre fiction. "That used to be a real novelty act, or something that was done with kid gloves or with heavy irony," notes Lethem. "Now, a lot of writing has a very natural degree of engagement with the vernacular culture." Look at someone like Sittenfeld, whose Prep, a wildly readable account of a Midwestern girl floundering at an élite Eastern boarding school, became a surprise best seller. Is she a literary writer or a commercial writer? The distinction no longer seems to apply. She's just a good writer...