Word: priapism
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Dates: during 1990-1999
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...PRIAPISM Although it never happened in the trials, there is a theoretical risk that men with sickle-cell anemia, leukemia or urethral inflammation could, when taking Viagra, develop priapism (defined as an erection that lasts four hours or more). Untreated, priapism can lead to tissue damage and even impotence...
Johns Hopkins researchers say they have discovered what may be the essential signal that triggers erection: a tiny secretion of nitric oxide by penile nerves. An ointment that promotes the production of nitric oxide might alleviate impotence; one that inhibits production could relieve priapism, prolonged erections unrelated to desire. Also, if nitric oxide turns out to rouse the clitoris, medicated cream could help women reach orgasm...