Word: priore
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Dates: during 2000-2009
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...August, a team of scientists at Northwestern University were the first to show why the brain's "memory function" fails in the face of an insulin shortage. The group's prior research had already pinpointed the culprit: toxic proteins called amyloid beta-derived diffusible ligands (ADDLs, for short), which are known to pile up in the brains of people with Alzheimer's. Scientists also knew that Alzheimer's patients' brains have lower levels of insulin and are insulin resistant. But what the Northwestern team discovered is the molecular mechanism behind that resistance: when ADDLs bind to neurons at synapses, they...
...sunshine days are over. Tasked with selling an unpopular war and a weakened President to a skeptical audience, Perino is unlikely to make many buddies in the briefing room. Attempts to promote Bush's policies immediately collide with his 68% disapproval rating. At a recent briefing that took place prior to Bush's veto of the expansion of health-care funding for low-income children, Perino found herself in the unenviable position of arguing that Bush does not want children to suffer. As Congress and the courts push back on Bush's tactics for fighting terrorism, his advisers are struggling...
...development. Some have accused the administration of vacillating and keeping students out of the loop. Typically, however, changes in University Hall move at a snail’s pace. In this case, it appears that the administration quickly realized that it did not fully consider the implications of its prior statements and erred in announcing an overly broad policy. The administration’s actions also demonstrate that, despite what some conspiracy-minded students would like to believe, University Hall is not on a crusade to wipe out fun at Harvard. If that were the case, administrators would not have...
...With the world watching, tournament officials enforce stringent rules. Traditionally, schoolyard tricksters harden their conkers by baking them or by soaking them in vinegar. To prevent such breaches, referees provide regulation conkers to competitors prior to each match. The Ashton Conker Club sources the chestnuts from trees within a five-mile radius - to account for regional variations in ripeness and, therefore, hardness - and they precision-drill each...
...Lawsuits aside, the game goes on, and the World Conker Championships endures. Tomos Smith, 23, a mechanical engineer who came dressed as a schoolgirl, had low expectations prior to the tournament, which was his first. "I just thought it'd be 20 people in a shed," he says. "But all in all it's been a cracking...