Word: profound
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...relentless pace of blockbuster deals is raising profound and disturbing questions. While economists generally praise mergers as good for the economy, many critics voice strong doubts. They charge that even the friendliest consolidations can derail careers, disrupt communities and create unmanageable mountains of debt. Perhaps worst of all, evidence is accumulating that many celebrated past mergers have been colossal failures. Warns Sigurd Reinton, a partner in the management-consulting firm of McKinsey & Co.: "The benefits of mergers and acquisitions are often overrated. You cannot generalize and say all acquisitions are bad, but there is a sufficient number that, at least...
...AIDS to the use of "poppers" (liquid inhalants like amyl nitrite and butyl nitrite), which are said to enhance sexual pleasure and which had been used by many of the victims. Another theory held that repeated anal intercourse introduced sperm into the blood-stream and that this could cause profound immune suppression. Then there was the "immune-overload theory," which was based on the fact that many early AIDS patients were extremely active sexually, with hundreds of partners over the course of their lifetimes and long histories of venereal diseases and infections. Under the accumulated burden of so many infections...
...They are my representatives in the Houses, and have a profound influence on the lives of students. I want to be able to select the best people, from a wide range of backgrounds,” Gross wrote...
This has been a year of major anniversaries: the fall of Viet Nam ten years ago last April, V-E day 40 years ago last May. But no event has had as profound an impact on all our lives as the birth of the atomic age in the summer of 1945, and TIME felt it demanded special treatment...
...emotional high points of the album come through the recorded voices, which taken out of context, almost always become strangely profound. But this leads to the feeling that the songs are merely being overheard, that they are reporting something rather than making any statements—literally so in the case of “Venice,” a jokey play-by-play of an artist painting what seems to be an abstract crucifixion scene (complete with Italian voices and crowd noises...