Word: profound
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...influence of a teacher can be profound, somes far more than intended. So it was with the heritage of Hippocrates. Although a great many writings would be added to the literature of medicine over the next 1,800 years, they were largely restatements of, or small emendations to, the vast store of original findings in the Corpus...
...found their way to Boston, he might never have recovered. She has met other patients with his condition who went untreated for years, and they have not fared well. "Listening to patients," she says. "That's where Dr. Berde started. It seems elementary, but it's really so profound." The greatest tribute, however, is that Alex is thinking about a career in medicine. He spent this summer working for a Milwaukee anesthesiologist who trained under Charles Berde...
Both types of antidepressant had major side effects, though, including profound drowsiness and heart palpitations. The reason, scientists generally agreed, was that they affected brain chemistry too broadly. The research seemed to point to serotonin as the most important mood-enhancing chemical, though not the only one, and so neurochemists set about looking for a drug that would boost the influence of serotonin alone. In 1974, after a decade of work, Eli Lilly came up with Prozac, first of the so-called selective serotonin reuptake inhibitors, or SSRIS, and it was finally approved...
...change was so profound it spooked me. I'd done some reading by then on neurotransmitters, and I wasn't entirely comfortable with the notion that human laughter is, at bottom, a chemical phenomenon. After hearing from several friends how much more relaxed I looked, some whip-wielding inner Puritan took over and convinced me that I should throw away my pills...
...Rick Moody's 1994 novel, is a time of profound unease--when '60s free love got to the suburbs, and the folks there knew they had to try it but didn't know how to enjoy it. Promiscuity became one more burden of middle-class life. And the climactic ice storm is nature's way of saying, Don't try this at home. "At first it comes down like water, really soft," says Lee, 42. "Suddenly it freezes and wraps everything. It adds weight to the objects, eventually causing them to shatter. It's a crystal world...