Word: profoundly
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...think I have a little bit of a problem with the notion of meltdown,” he said. “I think what we have just gone through is a profound, challenging adjustment...
...thrashing defeat and recognize their failure," said 2007 Socialist presidential candidate Ségolène Royal, who triumphed in the Poitou-Charentes region. "The French people have spoken, and I believe they must be heard," echoed Socialist Party leader Martine Aubry. "Hearing the French people tonight means a profound change in policies...
...profound question for Republicans is whether they continue on the path of intransigence or decide to participate in the government. Intransigence has its pleasures. In the hermetically sealed tornado of right-wing bloviation, the wildest claims have come to seem the most marketable. This was a problem on the left for a long time. When Congressman Randy Neugebauer of Texas screamed "Baby killer!" on the House floor, the epithet resonated - the protesters who screamed those same words at U.S. troops in the 1960s sent the American pendulum swinging back toward conservatism and crippled the Democratic Party for several generations...
...specifically altering genes in the progenitive bone cells of mice, the researchers were able to observe a profound disruption of blood formation...
...arson attack a few years ago. I am taking this opportunity to re-read Dr. Martin Luther King Jr.'s classic book, Where Do We Go From Here: Chaos or Community? This was King's final book, written the year before his assassination, at a time of profound transition—not only for the black freedom struggle he helped to lead, but also for a nation still struggling to overcome the burdens of its complex history. This was King's deepest meditation on the intersecting crises of racism, poverty, and war, and it offers a prophetic roadmap...