Word: progenitor
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Snyder and Wolfe reversed the disease's progression by transplanting immature healthy brain cells, called progenitor cells, into the enzyme-deficient brains of newborn mice. According to Snyder, the young cells matured into normal healthy cells, migrating and engrafting themselves in the brain as the mouse grew older...
Researchers therefore decided to inject neural progenitor cells into the brain ventricles, chambers filled with cerebrospinal fluid surrounding the brain...
...Progenitor cells give rise to two types of brain cells, the neurons (nerve cells) and the glial cells (nourishing cells), which develop into specialized brain structures...
...time the newborn mice reached maturity, the neural progenitor cells had secreted the missing enzyme, engrafted throughout the brains and appeared as normal constituents of the central nervous system...
...researchers' work suggests that neural progenitor cells could eventually be used to treat Sly Disease in humans...