Word: progestin
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...Pill on the U.S. market today contains two synthetic chemical components, one resembling the natural female hormone estrogen, the other a progestin that resembles progesterone, which women secrete chiefly during pregnancy. Some are combinations in which both the estrogen and the progestin are taken for 21 days a month; others are "sequentials," in which the estrogen alone is taken for 14 to 16 days, and estrogen with progestin for five...
...Manhattan, at city-owned Metropolitan Hospital, Dr. Elizabeth B. Connell has had more than 1,000 women, some for as long as four years, taking a pill consisting only of chloramadinone, a progestin, every day of the year. Side effects seem to be fewer and less severe than those from pills containing estrogens, and the number of unwanted pregnancies has been negligible. The remarkable thing about these pills is that most women taking them still ovulate regularly, and so are theoretically exposed to conception. For reasons unknown, conception does not occur...
...similar progestin is being tested by the Upjohn Co. in a novel form. Upjohn technicians have made vaginal rings of Silastic (silicone rubber) impregnated with medroxyprogesterone (Provera). The rings are of the same spring-reinforced design as the ring of a diaphragm, but there is no cap. The woman inserts the ring five days after the beginning of a menstrual period, removes it after 21 days, and throws it away. She should menstruate within two days, and start the 28-day cycle again with a new ring five days later...
...THROMBOPHLEBITIS. Women on 20-day pills that combine a progestin (a synthetic that acts like a pregnancy hormone) with a minute quantity of estrogen react as though they were "a little bit pregnant." Changes in the blood resemble those of pregnancy-including, for some women, an increased tendency for blood clots to form in inflamed leg veins. From there, they may travel to the lungs. A committee on drug safety studied every suspected case it could find in Britain and concluded that a woman taking such pills "incurs a slightly increased risk of developing thromboembolic disorders, but that risk...
...father of birth control pills; of myeloid metaplasia, a blood disease; in Boston. A brilliant biologist, Pincus first won national attention in 1939 by inducing a "fatherless" mammalian birth (a lab-fertilized rabbit egg); then in the 1950s, with Harvard Gynecologist John Rock, successfully tested an ovulation depressant called progestin, which came on the market in 1960 as Enovid. At his death, Pincus was testing yet another idea: a "morning after" pill, which keeps fertilized eggs from settling in the womb...