Word: pronuclei
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Dates: during 1970-1979
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...this technique, devised by Yale Biologist Clement Markert, eggs are removed from a female mouse shortly after fertilization. At this early stage, genetic material from egg and sperm have not yet mixed; the mother's and father's genes are still in two distinct sacs, called pronuclei. Using microsurgery, Markert removes either pronucleus. The egg is then exposed to a chemical that causes the remaining pronucleus to replicate, thus giving the cell a full complement of genes. Then the cell itself divides, and the resulting embryo is placed in the uterus of a female mouse to develop. Using...
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