Word: prostacyclin
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Dates: during 2000-2009
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...scientists thought. Animal studies suggest that COX-2 also promotes chemical reactions that churn out prostacyclin, a protein that keeps blood vessels dilated and keeps platelets from clumping together to form blood clots. Doctors believe a drop in prostacyclin may also be behind the increased incidence of heart attacks and strokes in COX-2 users. In separate studies published in the New England Journal of Medicine last week, researchers found that high-dose Celebrex users were three times as likely as nonusers to die from a heart or stroke event, while those taking Vioxx had twice the chance of suffering...
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