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...mentally stimulating activity, socializing frequently and exercising may help protect against age-related decline - at least cognitive decline. As early as 1995, neuroscientist Carl Cotman, who studies aging and dementia at the University of California at Irvine, published a paper in Nature showing that physical exercise produces a protein that helps keep neurons from dying and spurs the formation of new neural connections in the brain. More recently, Cotman demonstrated in studies of elderly dogs and mice that enriching their social environment is associated with improvement in brain function...

Author: /time Magazine | Title: In Old Age, Friends Can Keep You Young. Really | 6/24/2009 | See Source »

...test is based on a protein excreted in the urine by patients who have an infection in the appendix. Led by Dr. Richard Bachur, chief of emergency medicine at Children's Hospital Boston, researchers discovered the hallmark protein by collecting and analyzing urine samples from 12 pediatric patients with confirmed cases of appendicitis (determined by inspection of the appendix after surgery). From an initial result involving thousands of different proteins, researchers narrowed the potential candidates by comparing the 12 samples to those from healthy children without appendicitis. "We analyzed the proteins to see which were statistically significant compared with...

Author: /time Magazine | Title: A Urine Test for Appendicitis | 6/23/2009 | See Source »

...those, 25 were confirmed to have the sharply painful condition; samples from the other patients were used as controls. Steen explains that in an emergency room situation, physicians are often faced with distinguishing appendicitis from conditions involving abdominal pain, so it made sense to mimic this contrast in the protein analysis as well...

Author: /time Magazine | Title: A Urine Test for Appendicitis | 6/23/2009 | See Source »

...reason for LRG's accuracy may have to do with its origin. Kentsis explains that the protein is specific to the immune cells that characterize appendicitis, and is likely a direct result of the infection, unlike other proteins that may be produced in a biological chain reaction, stemming from but distant to the original infection. "It makes good biological sense why LRG would be elevated in patients with appendicitis," he says...

Author: /time Magazine | Title: A Urine Test for Appendicitis | 6/23/2009 | See Source »

...typical day in his Kirkland suite, Michael “Mikey” J. Friedman ’11 could be found singing “Hakuna Matata,” playing with the protein modeling computer program Pymol, or coming up with some harebrained scheme to entertain and distract his friends, they said. The aspiring oncologist passed away in early October at the age of 19, bringing an end to his four-and-a-half year battle with desmoplastic small round cell tumor, a rare and aggressive form of cancer. Friends and family said that Friedman exuded brightness?...

Author: By Aditi Balakrishna, CRIMSON STAFF WRITER | Title: Michael J. Friedman '11 | 6/4/2009 | See Source »

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