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Word: psychopharmacologists (lookup in dictionary) (lookup stats)
Dates: during 1990-1999
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Biochemically, hypericum has some interesting properties. For starters, says University of Frankfurt psychopharmacologist Walter Muller, it appears to affect the brain in the same way Prozac does--by prolonging the activity of the mood-enhancing brain chemical serotonin. This is the same neurotransmitter acted on by the controversial diet pills fen-phen and Redux (see following story). But hypericum has much broader activity. In rats and mice, at least, it extends the action of at least two other powerful brain chemicals that are thought to play a role in depression: dopamine and norepinephrine. In each case, hypericum appears to work...

Author: /time Magazine | Title: ST. JOHN'S WORT: NATURE'S PROZAC? | 9/22/1997 | See Source »

...quickly withdrawn six years later, after Finnish doctors reported that eight patients taking the drug had died of agranulocytosis, a sudden loss of infection-fighting white blood cells. In the U.S., the Food and Drug Administration halted even preliminary tests. "We assumed it was a dead product," recalls psychopharmacologist Gilbert Honigfeld, who helped develop the drug for Sandoz and is now in charge of marketing it in the U.S. American and European research eventually showed that agranulocytosis occurred in 1% to 2% of clozapine patients and that it could be detected and nipped in the bud by conducting blood tests...

Author: /time Magazine | Title: Awakenings : Schizophrenia: A New Drug Brings Patients Back to Life | 7/6/1992 | See Source »

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