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...years, many stem-cell researchers sought to accomplish that through nuclear transfer-transplanting an adult cell's nucleus into an egg that had been emptied of its own genetic material. This process is expensive and difficult, and so far no one has been able to pull it off in humans. Yamanaka never tried. Starting with a tiny team in 1999 at the Nara Institute of Science and Technology-he moved to Kyoto in 2004-Yamanaka focused on finding the genes that could persuade an adult cell to regress on its own to an embryonic state, without the messy mechanics...

Author: /time Magazine | Title: Ahead of the Curve | 6/14/2007 | See Source »

...spending more time in America later this year-he has accepted a post as a visiting scientist at the J. David Gladstone Institute in San Francisco. But his overseas travels will be limited. Yamanaka says he'll remain based in Japan because he doesn't want to pull his children out of high school. He has also been a father figure to younger colleagues-one that isn't afraid to share the credit. "He's a guiding teacher," says Kazutoshi Takahashi, an assistant professor at Kyoto and Yamanaka's first student. "Everyone in the lab gets the opportunity to have...

Author: /time Magazine | Title: Ahead of the Curve | 6/14/2007 | See Source »

With his control of Gaza crumbling, Abbas' only weapon is to pull out of the "unity" government with Hamas, saddling the Islamic militants with tighter international sanctions. It's a desperate tactic, but Hamas officials say they are in no mood to negotiate with Abbas. Gaza locals say Hamas has prepared a list of Fatah leaders to either arrest or execute, a move that would make a diplomatic compromise that much less likely...

Author: /time Magazine | Title: Hamas' Takeover of Gaza | 6/14/2007 | See Source »

Rogen and Carell are two examples of underknown talents with ordinary looks who were given lead roles in movies and instantly proved their pull as comedy stars; they could make the audience fall in laugh with them. Just now, they are two of a dozen or so movie comics who are giving the genre a clout it hasn't seen for decades--maybe since the great silent era of Charlie Chaplin, Buster Keaton and Harold Lloyd. Will Ferrell, Ben Stiller, Adam Sandler, Vince Vaughn and their jolly colleagues aren't of Chaplin's artistic stature, but they are something...

Author: /time Magazine | Title: Comedians' Little Secret | 6/14/2007 | See Source »

...singer was only 4' 8") and she acts neurasthenic as all get out, but somehow her constantly victimized state works against our sympathetic response, particularly since the film's random structure often robs us of cause-effect connections. Sometime an inner voice threatens to burst forth: "C'mon Edie, pull up your socks...

Author: /time Magazine | Title: A Very Dreary Vie En Rose | 6/8/2007 | See Source »

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