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Matured T cells have been taught to locate invaders which express the receptor for the M-tropic strain. Those that are not able to spot invaders--native T cells--express the receptor for the T-tropic strain...

Author: By Ayanna A. Lonian, | Title: HMS Faculty Isolate Secondary Strain of HIV | 3/5/1997 | See Source »

...Before this was all really phenomenology. Nobody really had any way of relating this to a basic mechanism, a molecule, a co-receptor," Springer said in a press release...

Author: By Ayanna A. Lonian, | Title: HMS Faculty Isolate Secondary Strain of HIV | 3/5/1997 | See Source »

...There have been people identified because they are resistant to HIV, who have a mutation in the M-tropic receptor," he said. "That antibody could be therapeutic...

Author: By Ayanna A. Lonian, | Title: HMS Faculty Isolate Secondary Strain of HIV | 3/5/1997 | See Source »

...genetic variety was not meant to be. Researchers from the United States and Finland announced recently that, despite attempts to replicate the results in two groups of Finnish men, they did not detect any connection between novelty-seeking and the longer gene variant of the so-called dopamine D4 receptor gene that was purported to correlate with it. The conclusion of these researchers: "These data suggest that D4DR may require re-evaluation as a candidate gene for personality variation...

Author: NO WRITER ATTRIBUTED | Title: We're Not Just Genes | 11/9/1996 | See Source »

Many psychoactive drugs--including opiates, the Valium-type compounds and angel dust--mimic the action of neurotransmitters by binding to particular receptors and influencing the neuron's firing. Pharmacologists have acquired the tools to screen new drugs quickly, testing their affinity for particular receptors by cloning, or duplicating, the receptors and then designing molecules that bind to them. So refined are the new techniques that scientists now know of 14 different receptors for serotonin, the ubiquitous chemical messenger that plays a critical role in sleep, mood, depression and anxiety. They have also discerned five different receptor subtypes for dopamine...

Author: /time Magazine | Title: TARGETING THE BRAIN | 9/18/1996 | See Source »

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