Word: receptors
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...RECEPTOR ANTAGONISTS...
Tamoxifen is a selective estrogen receptor modifier, a type of drug that prevents estrogen—a key player in breast cancer— from binding to cells in breast tissue...
...blueberries, could be the foundation of a natural remedy to reduce cholesterol. In head-to-head lab studies against a cholesterol-lowering drug, pterostilbene was just as active as the pharmaceutical in dampening the cholesterol-producing functions of rat liver cells. And because pterostilbene targets a specific lipid-triggering receptor, scientists anticipate that it will have fewer side effects...
...other categories of medications include beta-blockers, which moderate heart rate and the angiotensin system; calcium-channel blockers, which obstruct the tiny ducts in cells through which calcium ions must pass to constrict blood vessels; ACE inhibitors, which reduce the production of angiotensin and thus reduce constriction; and angiotensin-receptor blockers, which allow the protein to be produced but prevent some of it from being taken up by the cells. All four of these have the same goal--to unclench the tensed circulatory system--and they are often prescribed in combination...
...University of California, San Francisco, meanwhile, molecular geneticist Cynthia Kenyon is taking a different approach to aging research, identifying a number of genes in roundworms that help stave off disease and extend life. One such gene directs the action of a receptor for insulin and an insulin-like hormone called IGF1, and by manipulating it along with other genes, she can increase the worms' life-span sixfold. "It's not so much that they're just living longer," she says. "What's remarkable about these worms is how healthy they...