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...already huge out here," he says. "Everyone wants to show their families they work for a big name." Recruiting at top Chinese universities, Leonhardt would show the swoosh and the bitten apple, logos the students readily recognize as Nike's and Apple's. "But when I showed them the red bull's-eye--silence," he says. He compensates by showing them Target's rank in the Fortune�500 (33rd...
...studies reported in Proceedings of the National Academy of Sciences, they sampled pints of donated blood from banks and healthy volunteers, subjected them to 26 different analyses and found dramatic deficiencies in levels of nitric oxide (NO). A workhorse component of normal blood, NO is responsible for helping red blood cells ferry oxygen to tissues and for propping open tiny vessels. A shortage of the gas could lead to precisely the kinds of heart problems the team was investigating...
...received a blood transfusion had a 25% chance of having a heart attack and an 8% chance of dying within 30 days; similar patients who did not get a transfusion had an 8% chance of a cardiac event and a 3% chance of death. Stamler believes that without NO, red blood cells are not dilating tiny vessels properly and instead pile up in the narrow passageways, blocking flow and damaging the very heart tissue the blood was transfused to help...
...this added risk, those percentages had already been disturbing enough to persuade physicians to change what is known as their transfusion trigger. As a rule, they introduced donated blood as soon as the patient's hematocrit--a measure of the proportion of the blood made up of oxygen-carrying red cells--fell below the normal range of 45%-55%. Lately, however, they have begun waiting until it drops to less than 30% before transfusing...
...shelves. Working with dogs, Stamler has shown that the heart-attack rate drops when depleted blood is replenished with liquid NO. Human premature babies born with underdeveloped lungs are already being exposed to gaseous NO to help their tissues get the oxygen they need. For now, the American Red Cross, which oversees the 14 million units of stored blood, is awaiting more studies before changing its processing and storage practices...