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Word: redux (lookup in dictionary) (lookup stats)
Dates: during 1990-1999
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...would they? After all, other serotonin enhancers, such as Prozac, have never caused heart problems. There is a crucial difference, however, between Prozac and Redux-fenfluramine. The former, like the other SSRIS, keeps serotonin in circulation longer than it would otherwise be, thus helping the brain get the most out of its normal output. The latter do the same, but they also force nerve cells to boost the levels of serotonin that go into circulation. It is this unnatural bath of excess serotonin, some scientists theorize, that causes heart-valve defects and also triggers brain damage--in monkeys...

Author: /time Magazine | Title: THE MOOD MOLECULE | 9/29/1997 | See Source »

...Redux and fenfluramine are too powerful for the body to handle--a proposition not fully accepted by some doctors despite the FDA and manufacturers' action--research into serotonin-boosting drugs is hardly slowing down. If anything, the discovery of a new set of side effects will spur researchers to hone their pharmacological handiwork even more, to create medicines that will not just fine-tune the way serotonin is used in the brain but might target specific serotonin receptors as well or act on only specific parts of the brain and nervous system...

Author: /time Magazine | Title: THE MOOD MOLECULE | 9/29/1997 | See Source »

...finger pointing that followed last week's abrupt withdrawal of two of the country's favorite diet pills looked like a multiple-choice law-school torts exam, the similarity was hardly coincidental. Even before the FDA urged the recall of Redux (dexfenfluramine)--and Pondimin (fenfluramine), the front half of the fat-pill combo known as fen/phen--scores of lawyers across the nation had already started filing lawsuits. After the recall, the legal assault turned into a stampede. "Everyone saw money," says Jacoby & Meyers' Gail Koff...

Author: /time Magazine | Title: WHO'S TO BLAME FOR REDUX AND FENFLURAMINE? | 9/29/1997 | See Source »

...seeking any individuals who felt they had been hurt by the capsules. New York lawyer Paul Rheingold, author of four suits so far, describes the diet-pill debacle as such "easy" pickings that he expects "many thousands of lawsuits scattered all around the country." Eventually, say some analysts, the Redux-fenfluramine recall could grow into one of the biggest medical-liability cases in history, perhaps exceeding the anticipated $2.4 billion from silicone breast implants...

Author: /time Magazine | Title: WHO'S TO BLAME FOR REDUX AND FENFLURAMINE? | 9/29/1997 | See Source »

Much of this legal furor is being vented against Wyeth-Ayerst Laboratories, a subsidiary of American Home Products, which makes fenfluramine and distributes dexfenfluramine, and Interneuron Pharmaceuticals, a small Lexington, Mass., firm founded by the M.I.T. neurologist who developed Redux. There's also talk of bringing action against the FDA--though federal law usually protects government officials from suits challenging routine performance of duties like approving drugs. Whatever the outcome of the legal battles, they leave unsettled larger societal questions--about Americans' infatuation with quick-fix remedies for whatever ails them, real or imagined, and their doctors' willingness to cater...

Author: /time Magazine | Title: WHO'S TO BLAME FOR REDUX AND FENFLURAMINE? | 9/29/1997 | See Source »

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