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Scientists at Regeneron, based in New York, are tapping into the same feeding hub in the brain but through a different protein that is more closely related to leptin. Regeneron's agent, Axokine, fools the brain into thinking that the body's fat stores are well stocked, short-circuiting the need to eat. People who took Axokine and stayed on a low-calorie diet and exercise program lost twice as much weight as those who relied on diet and exercise alone...

Author: /time Magazine | Title: America's Obesity Crisis:Pills in the Pipeline | 6/7/2004 | See Source »

...obesity may take, one thing is clear: the most effective treatments will probably involve a mix of agents chosen to match each patient's needs. "A few years ago, we were all looking for a single magical cure for all obesity," says Dr. George Yancopoulos, chief scientific officer of Regeneron. Now the answer seems more likely to come, as weight loss usually does, one hard-fought-for step at a time...

Author: /time Magazine | Title: America's Obesity Crisis:Pills in the Pipeline | 6/7/2004 | See Source »

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