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...researchers untangle the complex genetics of autism. Now that effort is beginning to pay off. The largest genetic study of autism ever attempted - involving more than 3,000 participants from AGRE, 1,453 cases from other sources and over 7,000 additional control subjects - identified genetic variations in a region of chromosome 5 that appears to play a pivotal role in about 15% of cases of autism. What makes this region particularly fascinating is that it seems to regulate gene-coding for proteins that are essential to forming connections in the brain. This fits well with earlier research - including imaging...

Author: /time Magazine | Title: Autism Linked to Genes That Govern How the Brain Is Wired | 4/28/2009 | See Source »

...study, published in the current issue of Nature, focused on a region of DNA that codes for two proteins called cadherin 9 and 10. These are sticky substances involved in a process known as neuronal cell adhesion. "They sit at the synapse, and when the nerves come together, these molecules adhere to the nerve," essentially fusing a connection in the brain, explains Dr. Hakon Harkonarson, director of the Center for Applied Genomics at the Children's Hospital of Philadelphia (CHOP) and a lead author of the study. Preliminary research suggests that cadherin 10 is very active in wiring the frontal...

Author: /time Magazine | Title: Autism Linked to Genes That Govern How the Brain Is Wired | 4/28/2009 | See Source »

...perhaps not on a human time scale. In one recent research project, Mukhopadhyay used noble gas concentrations in ocean coral off the coast of Africa as a way of tracking how dust emission rates have changed in response to climate variation. Because the drying of the Northern African Sahel region has caused widespread famine in recent decades, Mukhopadhyay says his research may be useful in understanding how further climate change will affect the region in the future. In addition to being an incisive and broad-ranging researcher, Mukhopadhyay also teaches Earth and Planetary Sciences 7, the department?...

Author: By Peter F. Zhu, CRIMSON STAFF WRITER | Title: 15 Faculty Hot Shots: Sujoy Mukhopadhyay | 4/28/2009 | See Source »

...While Teach for America participants receive salaries which vary from region to region,” said Lumumba B. Seegars ’09, a campus representative for Teach for America, “These AmeriCorps funds provide educational grants to participants in national service to pay off previous loans...

Author: By Marc G. Steinberg, CONTRIBUTING WRITER | Title: Federal Funds To Boost Service | 4/28/2009 | See Source »

...protesters converged on Tbilisi on April 9, calling for President Mikheil Saakashvili to resign over his mishandling of last year's conflict with Russia. The demonstrators, representing a wide range of opposition parties, criticized Saakashvili's lavish lifestyle and his defeat in the war over the breakaway region of South Ossetia. Some threw carrots and cabbage at the presidential residence, released a live rabbit (to represent, they said, his rabbitlike cowardice against Russia) and mocked him in political theater performances. But after a week, the number of protesters had dwindled to fewer than 20,000. Saakashvili has so far refused...

Author: /time Magazine | Title: The World | 4/27/2009 | See Source »

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