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...brain region that drew the attention of the authors is known as the locus coeruleus, a small knot of neurons located in the brain stem. Not a lot of high-order processing goes on so deep in the brain's basement, but the locus coeruleus does govern the release of the neurotransmitter noradrenaline, which is critical in triggering arousal or alarm, as in the famed fight-or-flight response. Arousal also plays a role in our ability to pay attention - you can't deal with the lion trying to eat you, after all, if you don't focus...

Author: /time Magazine | Title: Why Fever Helps Autism: A New Theory | 4/7/2009 | See Source »

...Nobody recommends inducing fevers to kick-start the locus coeruleus, since that could lead to all manner of side effects and other ills. Instead, Mehler and Purpura believe the likeliest answer is in medications that target noradrenaline brain receptors. "First, we should look at the signaling pathways in the region of the brain involved," Purpura says. "Then we could look at treating the receptor sites with some kind of pharmacotherapy." For once, the step that's missing from a proposal is the one that involves shouting about what's to blame...

Author: /time Magazine | Title: Why Fever Helps Autism: A New Theory | 4/7/2009 | See Source »

...Belfast Violence Reawakened Twelve years after the last killing of a British soldier in Northern Ireland, two deadly shootings in as many days threatened to reignite the violence that once plagued the region. On March 7, two British soldiers were killed in an ambush while accepting a pizza delivery at an army base near Belfast, an attack for which the dissident splinter group the Real IRA claimed responsibility. Just two days later, a policeman was murdered while sitting in his unmarked patrol car. A separate faction, Continuity IRA, said it had orchestrated the killing; two suspects have been arrested. Some...

Author: /time Magazine | Title: The World | 4/7/2009 | See Source »

...Washington has been an abject failure at defending our border.' RICK PERRY, saying the Lone Star State will simply have to "take care of itself." Obama later agreed to send 37 federal agents to the region...

Author: /time Magazine | Title: Verbatim | 4/7/2009 | See Source »

...leader," has been sought by the Sri Lankan authorities ever since the 1976 murder of Alfred Duraiappah, then mayor of the northern city of Jaffna. But until now he has eluded capture in his jungle hideaways and, reportedly, on occasional clandestine trips to other parts of the region. "He is surrounded by the army," says Vinayagamoorthi Muralitharan, previously known as Colonel Karuna when he served as the LTTE's eastern military commander. "It is now almost impossible to escape undetected. All the top Tiger leaders are still very much in the Vanni [the region where the fighting is taking place...

Author: /time Magazine | Title: Sri Lanka Closes In on Leader of the Tamil Tigers | 4/6/2009 | See Source »

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