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...detect brain activity during REM sleep in his laboratory at the Massachusetts Mental Health Center, Hobson uses electroencephalograms (EEG). He says measurements of the brain's electrical output, made by attaching electrodes to the head, show that the brain is almost 90 percent more active during REM sleep than at any other slumber time. The normal human passes through five distinct stages of sleep, with the REM stage following the lighter, first two stages. Sleep stages three and four--following REM chronologically--are deep sleep periods...

Author: By Katherine E. Bliss, | Title: Sweet Dreams...? | 3/18/1988 | See Source »

...from Harvard in 1959. "Nobody had ever studied the electrical activity of the individual [brain] cells during sleep. What we did was use microelectrodes in the brain to see what was going on. We put them under the bone and aimed them at the cells where we thought REM was occuring and put an object on the bone to measuere the output...

Author: By Katherine E. Bliss, | Title: Sweet Dreams...? | 3/18/1988 | See Source »

...learned that some neural cells had a preference for being 'on' [processing hormones] during awake time, and some were always 'on' during sleep. But some of the 'awake' cells turn 'on' while in REM sleep," he says...

Author: By Katherine E. Bliss, | Title: Sweet Dreams...? | 3/18/1988 | See Source »

...What we began to notice was that there was an [activation of some of the] neurons during sleep, perhaps causing REM," he says...

Author: By Katherine E. Bliss, | Title: Sweet Dreams...? | 3/18/1988 | See Source »

Hobson and McCarley, who are both associated with the Department of Psychiatry at the Medical School, also tried to add to their dream model by analyzing the chemicals processed in the brain during REM sleep and then studying differences in the way various hormones direct sleeping versus waking activities...

Author: By Katherine E. Bliss, | Title: Sweet Dreams...? | 3/18/1988 | See Source »

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