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...grew as the virus continued to baffle scientists. Expecting the unexpected was the best way to confront HIV, he soon learned, and he quickly amassed an impressive array of scientific firsts in the field. As director of ADARC, which was founded in 1991 and was one of the first research centers dedicated solely to the study of AIDS, he led a team that pioneered the "hit 'em early and hit 'em hard" approach to drug therapy, now the core of the ARV-cocktail treatment that is keeping millions of HIV-positive patients alive. His lab showed how HIV therapies would...

Author: /time Magazine | Title: David Ho: The Man Who Could Beat AIDS | 1/25/2010 | See Source »

Without an answer, developing vaccines is a very halting process. "The virus is a moving target," says Dr. Gary Nabel, director of the Vaccine Research Center at the National Institutes of Health (NIH). "It is constantly changing its genetic makeup through mutations. It's also a moving target because the proteins of the virus surface are actually moving themselves - they are conformationally flexible. The net result is that the immune system never gets a really good look at them...

Author: /time Magazine | Title: David Ho: The Man Who Could Beat AIDS | 1/25/2010 | See Source »

SOURCE: TIME RESEARCH...

Author: /time Magazine | Title: The World | 1/25/2010 | See Source »

...This shows that PTSD is a brain disease," says Dr. Apostolos Georgopoulos, who led the research along with Brian Engdahl and a team from the Brain Sciences Center at the Minneapolis VA Medical Center and University of Minnesota. "There have been questions that this is a made-up disorder and isn't a true brain disease, but it is." Just as importantly, he says, the magnetic-imaging biomarker shows changes over time in a brain's electrical activity, allowing mental-health workers to chart the effectiveness of various therapies. "It will be a tremendous tool in monitoring treatment," he says...

Author: /time Magazine | Title: Study Points at a Clear-Cut Way to Diagnose PTSD | 1/25/2010 | See Source »

...PTSD research builds on earlier work that showed MEG could be used to detect Alzheimer's and multiple sclerosis in infected brains. "These communication patterns are very different from disease to disease," Georgopoulos says. "So the different diseases create disturbances in the communication that can be used as a fingerprint, a signature, for the disease." He likens the MEG test for PTSD to the blood-glucose monitoring tests regularly done by diabetics to keep their disease under control. Such testing, he adds, could be done by PTSD patients to monitor their progress. "The test is totally safe - there...

Author: /time Magazine | Title: Study Points at a Clear-Cut Way to Diagnose PTSD | 1/25/2010 | See Source »

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