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...these outcomes could reflect the influences of genes and other environmental influences - beyond those occurring in childhood - the tight relationship between increasing ACE numbers and increasing health risks makes the role of child trauma clear. Dr. Jack Shonkoff, director of Harvard's Center on the Developing Child, calls the research "a tremendous contribution...

Author: /time Magazine | Title: How Childhood Trauma Can Cause Adult Obesity | 1/5/2010 | See Source »

...simply can't remember it all. The solution, he outlines in his new book, The Checklist Manifesto: How to Get Things Right, isn't fancier technology or more training. It's as simple as an old-fashioned checklist, like those used by pilots, restaurateurs and construction engineers. When his research team introduced one in eight hospitals in 2008, major surgery complications dropped 36% and deaths plunged 47%. Gawande talked to TIME about why checklists work, what's wrong with medical school and what's next for health care reform. (See TIME's Wellness blog...

Author: /time Magazine | Title: Atul Gawande: How to Make Doctors Better | 1/4/2010 | See Source »

That makes it tough for Sisson to cheat, which she says is a "good thing." Last year, she signed up for stickK.com, a site founded by Yale economics professor Dean Karlan, whose research has shown that signing commitment contracts and publicly announcing a goal helps people stick to it. (The extra K in stickK is shorthand in legal writing for "contract.") Users are not required to wager any money when they sign up, but the serious ones do. Some 30% fork over their credit card information upfront and specify how much money should be automatically charged if they fail...

Author: /time Magazine | Title: A New Weight-Loss Plan: Getting Paid to Shed Pounds | 1/4/2010 | See Source »

...research on the origins of the fatal cancer suggest that methods for rapid diagnosis and even a vaccine against the disease may be possible. Reporting in a paper published in the Jan. 1 issue of Science, an international team of researchers based in Australia and New York State performed a genetic analysis of DFTD and found that it likely began in the devil's Schwann cells, a type of tissue that protects nerve fibers. Researchers have also identified genetic markers for the disease, which should allow doctors to distinguish facial tumor disease easily from other cancers that afflict the Tasmanian...

Author: /time Magazine | Title: Decoding the Tasmanian Devil's Deadly Cancer | 1/1/2010 | See Source »

...devils will eventually need a vaccine, and there is hope that this research may help scientists develop one. The team compiled a catalog of devil genes that affect the tumor and may contribute to its growth; these could be useful targets for designing a future vaccine. The difficulty will be creating a treatment that attacks the tumor, but spares healthy cells. "The key in a vaccine is not to create immune action that would hurt the devils by attacking their Schwann cells," says Papenfuss. "Now we can look for specific markers on the tumor cells to attack." Tough as they...

Author: /time Magazine | Title: Decoding the Tasmanian Devil's Deadly Cancer | 1/1/2010 | See Source »

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