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...medication that is incredibly effective at reversing overdoses," says Dr. Wilson Compton, director of the Division of Epidemiological Services and Prevention Research for the National Institute on Drug Abuse. "It makes good logical sense. I wish we had a rigorous evaluation of the benefits and potential risks...
While dramatic tales are many, it's still not clear how effective naloxone programs are overall. Research on their impact has only just begun. One study, published in the Journal of Addictive Diseases in 2006, found that after increasing for years, heroin-overdose deaths in Chicago dropped 20% in 2001, the year Bigg's program began, and fell an additional 10% the following year. So far, addiction researchers say no significant problems have been reported with naloxone use, but they concede that much more studying needs to be done...
Still, the rapid pace of the research means we may not have to wait long. "We really lucked out," says Lanza. "These iPS cells were just discovered a few years ago, and here we are three years later with a method safe enough to actually use in people." ACT plans to file a request for the first human trial using its cells sometime next year...
...findings may herald a practical solution to the problem of embryonic stem cells, the controversial cells that can be derived only from embryos (researchers currently use embryos that have been discarded during fertility treatments). President Obama recently lifted the long-standing ban on federal funding of human-embryonic-stem-cell research, but still, these stem cells are unlikely to prove useful as human treatments - for maladies like diabetes, Parkinson's or spinal-cord injuries - since they would not be tissue-matched to the individual patients who need them. The new method could allow scientists to create stem cells using...
...researcher working for a government agency that manages the old communist regime's secret police records stumbled across the new information as she was carrying out research on another project. The former West Berlin cop, Karl-Heinz Kurras, has a bulging Stasi file of some 7,000 pages. Kurras, it turns out, was a member of the East German SED Communist Party as well as an active Stasi agent. He joined the West Berlin police at the age of 22 in 1950, but five years later he switched sides and went to the authorities in East Berlin. Kurras wanted...