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...much impact this would have on patient care remains to be seen," says Dr. Sundeep Khosla, a professor of medicine at the Mayo Clinic, who wrote an editorial accompanying the two studies in the Journal. But because denosumab did not result in any serious side effects, it has the potential of becoming a safer alternative, should its current profile hold up in additional studies...

Author: /time Magazine | Title: Experimental Drug Helps Treat Osteoporosis | 8/11/2009 | See Source »

...agent works a little differently than the bisphosphonates, which are designed to paralyze bone-destroying cells - cells that increase in number as people age. While the body continually destroys and replaces bone tissue throughout life, the destruction eventually begins to overtake the construction, and the result in older age is a patchier, weaker type of bone that is more prone to breaking. While bisphosphonates block the activity of bone-destroying cells, denosumab prevents new ones from forming altogether. The end result is a tipping of the bone balance away from bone destruction and toward bone formation. Early studies in mice...

Author: /time Magazine | Title: Experimental Drug Helps Treat Osteoporosis | 8/11/2009 | See Source »

...state last year. But too many buyers, after discovering what a large and expensive chore caring for these snakes can be, simply get rid of them. And because there aren't a lot of adopt-a-python agencies, the reptiles are often dumped in the wild. As a result, Florida in 2008 instituted new ownership requirements, such as $100 annual permits, proof of snake-handling skills and implantation of microchips in pythons' hides to keep tabs on the snakes...

Author: /time Magazine | Title: Postcard from The Everglades | 8/10/2009 | See Source »

...appears to be a lost cause. The price of a sports watch she wants is $69.97, and the retailer is sticking to it. Yet Gault refuses to give in and offers this Hail Mary: "Is there a box for that watch? If not, can you shave something off?" The result: no box, a 10% discount and a reminder to always make sure no fixin's are missing. Since retailers can't afford to lose you these days, no demand is too peculiar...

Author: /time Magazine | Title: In the Recession, Shoppers Are Becoming Hagglers | 8/10/2009 | See Source »

...they are not just mere aberrations. Bollywood and elders now romanticize a time of close-knit familial relations that seems impossibly forced, even for the olden times. The realities of family rifts are often rewritten in golden age retellings of the joint-family collective memory, or dismissed as the result of wayward relatives and brash younger generations. Surely Dhirubhai Ambani may be rolling over in his grave, but today’s evidence for familial breakdown is rooted in themes of family disputes that are as timeless as “The Mahabharata.” Quarrelling families...

Author: By Ashin D. Shah | Title: Divide | 8/10/2009 | See Source »

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